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Strategically positioned in the midst of vibrant Downtown Roanoke, this two unit 4,400 SF building seamlessly blends historic charm with modern convenience and presents an exceptional opportunity for investors. As Downtown Roanoke is home to more than 900 business and 2600 residents, 22 Campbell Avenue SE is accessible and highly visible. The glass-front first floor is configured as a street-level retail space that includes a half restroom and is leased to The Market Gallery through March 31, 2030. The second floor has been renovated into an attractive, modern 2bd/2bth residence (2021) and will be available for new occupancy as of February 1, 2026. Recessed lighting, granite and hardwoods throughout, with the potential to develop a rooftop deck.